著者

Nao Yoshihiro Kazu Amimoto Shinpei Osaki Junpei Tanabe

出版者

社団法人 日本作業療法士協会

雑誌

Asian Journal of Occupational Therapy (ISSN:13473476)

巻号頁・発行日

vol.19, no.1, pp.213-222, 2023 (Released:2023-10-20)

参考文献数

37

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Background: Functional electrical stimulation (FES) improves unilateral spatial neglect (USN). However, only few studies have reported on the relationship between FES and cognitive function. Therefore, this study aimed to investigate the effects of FES on attentional function in healthy participants using the Posner task, which is generally used to assess patients with USN.Methods: In this interventional study, we conducted experiments on healthy participants to obtain fundamental knowledge before investigating effective ways of adapting FES to patients with USN as our final purpose. A total of 28 right-handed healthy young participants were assigned to the online-effect group or after-effect group and underwent FES simultaneously with or immediately before the Posner task, respectively. FES was applied to the extensor muscles of the left forearm to induce involuntary movement.Results: A significant difference was observed in the effects of FES in the Posner task between the online-effect group or after-effect group in the left-valid conditions (online-effect, 26.7 ms delay; after-effect, -0.4 ms [reduction]; p = 0.01). No interaction was noted between the groups and the type of target of the Posner task presentation condition. The effects of FES differed between the online- and after-effect condition groups.Conclusion: Performing the attention task after FES may enhance attention compared with performing the task with FES simultaneously.

著者

Toshihiko Ebisu Masaki Fukunaga Tomokazu Murase Toyoshi Matsuura Naoya Tomura Yasuhiro Miyazaki Shinpei Osaki Tsutomu Okada Toshihiro Higuchi Masahiro Umeda

出版者

Japanese Society for Magnetic Resonance in Medicine

雑誌

Magnetic Resonance in Medical Sciences (ISSN:13473182)

巻号頁・発行日

pp.mp.2022-0010, (Released:2022-04-02)

参考文献数

42

被引用文献数

1

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Purpose: To determine if functional connectivity measured with resting-state functional MRI could be used as a tool to assess unilateral spatial neglect during stroke recovery.Methods: Resting-state functional MRI was performed on 13 stroke patients with lesions in the right cerebral hemisphere and 31 healthy subjects. The functional connectivity score was defined as a correlation of a target region with the right inferior parietal lobule. Spatial neglect was measured with a behavioral inattention test.Results: First, the functional connectivity scores between the right inferior parietal lobule and right inferior frontal gyrus, including the opercular and triangular parts, were significantly decreased in stroke patients with unilateral spatial neglect compared with patients without unilateral spatial neglect and were significantly correlated with the behavioral inattention test score. Second, the functional connectivity scores between the bilateral inferior parietal lobules were also significantly decreased in patients with unilateral spatial neglect compared with patients without unilateral spatial neglect and were significantly correlated with the behavioral inattention test score. Third, negative functional connectivity scores between the right inferior parietal lobule and bilateral medial orbitofrontal cortexes, which are related to the default mode network, were detected in patients without unilateral spatial neglect in contrast to a reduction of this negative tendency in patients with unilateral spatial neglect. The functional connectivity scores between these regions were significantly different between patients with and without unilateral spatial neglect and were negatively correlated with the behavioral inattention test score.Conclusion: Though still in the pilot research stage and using a small number of cases, our findings are consistent with the hypothesis that functional connectivity maps generated with resting-state functional MRI may be used as a tool to evaluate unilateral spatial neglect during stroke recovery.