- 著者
- HIROSHI SUEMUNE YUKAKO MIZUHARA HIROYUKI AKITA TAKESHI OISHI KIYOSHI SAKAI
- 出版者
- The Pharmaceutical Society of Japan
- 雑誌
- Chemical and Pharmaceutical Bulletin (ISSN:00092363)
- 巻号頁・発行日
- vol.35, no.8, pp.3112-3118, 1987-08-25 (Released:2009-10-19)
- 参考文献数
- 16
- 被引用文献数
- 9 15
Asymmetric synthesis of platelet-activating factor (PAF) and its enantiomer by using biocatalysts was studied. Microbial reduction of the pro-chiral α-ketoester (3) afforded (+) -4 (> 99% ee), which could be converted to (+) -and (-) -batyl alcohol (12), a key synthetic intermediate for PAF. Compound (-) -4 (96% ee), with the requisite configuration for the synthesis of natural PAF, could also be obtained by enzyme-catalyzed enantioselective hydrolysis of (±) -15.
- 著者
- Ryoichi Ishikawa Bo Zheng Takeshi Oishi Katsushi Ikeuchi
- 出版者
- 一般社団法人 情報処理学会
- 雑誌
- IPSJ Transactions on Computer Vision and Applications (ISSN:18826695)
- 巻号頁・発行日
- vol.7, pp.89-93, 2015 (Released:2015-07-27)
- 参考文献数
- 12
The aerial 3D laser scanner is needed for scanning the areas that cannot be observed from the ground. Since the laser scanning takes time, the obtained range data is distorted due to the sensor motion while scanning. This paper presents a rectification method for the distorted range data by aligning each scan line to the 3D data obtained from the ground. To avoid the instability and ambiguity of the line-based alignment, the parameters to be optimized are selected alternately, and the smoothness constraint is introduced by assuming that the sensor motion is smooth. The experimental results show that the proposed method has the good accuracy simulation and actual data.