- 著者
- Takashi Ide
- 出版者
- Japanese Society for Food Science and Technology
- 雑誌
- Food Science and Technology Research (ISSN:13446606)
- 巻号頁・発行日
- pp.FSTR-D-23-00088, (Released:2023-10-11)
The combined effect of γ-linolenic acid (GLA)-rich evening primrose oil and soybean phospholipid on lipid metabolism was investigated. Male ICR mice were fed diets containing 100 g/kg of coconut, safflower or GLA oil, supplemented with 31 g/kg of soybean oil or 50 g/kg of soybean phospholipid, for 21 d. All experimental diets provided the same amount of fatty acids. The diets containing GLA oil significantly reduced hepatic triacylglycerol levels compared with those containing coconut oil. The values obtained from diets containing GLA oil also tended to be lower than those obtained from the diets containing safflower oil. Soybean phospholipid, regardless of the type of dietary fat, reduced hepatic triacylglycerol levels. Therefore, the combination of GLA oil and soybean phospholipid was effective in causing a marked decrease in hepatic triacylglycerol levels. Changes in hepatic fatty acid oxidation and lipogenesis may be responsible for the observed results.
- 著者
- Takashi Ide Ayana Azechi Sayaka Kitade Yoko Kunimatsu Natsuko Suzuki Chihiro Nakajima Naoki Ogata
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- pp.ess14182, (Released:2015-01-20)
- 被引用文献数
- 4 10
We compared the physiological activities of sesame seeds rich in lignans from three varieties (Gomazou, Maruhime and Maruemon), and those from a conventional cultivar (Masekin) in rats. The sum of the values of fat-soluble lignans (sesamin and sesamolin) in seeds of Gomazou, Maruhime and Maruemon varieties was approximately double the value in Masekin. Seeds from Maruemon contained fat-soluble lignan most exclusively as sesamin while other varieties contained sesamin and sesamolin at about a 2:1 ratio. After a 16 d experiment, sesame seeds, added at 200 g/kg to the experimental diets, increased the activity and mRNA levels of fatty acid oxidation enzymes. Increases were stronger with seeds rich in lignans than with seeds from Masekin. In contrast, sesame seeds lowered the activity and mRNA levels of lipogenic enzymes. However, sesame seeds from all the varieties were comparable in affecting these parameters. Serum triacylglycerol concentrations were lower in rats fed diets containing sesame seeds rich in lignans than in those fed a diet free of sesame seeds or a diet containing seeds from the Masekin variety. Serum malondialdehyde (a marker of lipid peroxidation) was lower in rats fed diets containing sesame seeds rich in lignans than in those fed a sesame seed-free diet or Masekin diet. It is apparent that sesame seeds rich in lignans, irrespective of lignan composition, more profoundly affect hepatic fatty acid oxidation and serum triacylglycerol levels and possibly attenuate oxidative stress. Therefore, consumption of sesame seeds rich in lignans hopefully results in physiological activity to promote health.