著者

Kazuhiro Kubo Mayu Kasumi Takatoshi Yamashita

出版者

Japanese Society for Food Science and Technology

雑誌

Food Science and Technology Research (ISSN:13446606)

巻号頁・発行日

pp.FSTR-D-23-00059, (Released:2023-07-27)

被引用文献数

1

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Hard water is softened because its use in everyday life can cause various problems in the living environment. However, existing water-softening methods have a number of drawbacks. Here we examined a new water-softening method involving atomization. Three concentrations of calcium-based synthetic hard water and a commercial natural hard water were prepared. Each hard water was sprayed into the atmosphere at 1 MPa from an atomization nozzle and then collected. Part of the collected water was recirculated, and the atomization treatment was continued. After the treatment, a white precipitate and fine bubbles were generated, the Ca2+ concentration and electrical conductivity decreased, and the pH increased. Then over time, the white precipitate increased slowly and the Ca2+ concentration decreased until finally it almost fell within the recommended range. This water-softening phenomenon was thought to be due to expansion of the gas-liquid interfacial area and generation of fine bubbles with atomization. This method is extremely simple and expected to show high versatility.

著者

Naoko INABA Toshiro SATO Takatoshi YAMASHITA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.61, no.6, pp.471-480, 2015 (Released:2016-02-12)

参考文献数

32

被引用文献数

34

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Vitamin K is essential for bone health, but the effects of low-dose vitamin K intake in Japanese subjects remain unclear. We investigated the effective minimum daily menaquinone-7 dose for improving osteocalcin γ-carboxylation. Study 1 was a double-blind, randomized controlled dose-finding trial; 60 postmenopausal women aged 50-69 y were allocated to one of four dosage group and consumed 0, 50, 100, or 200 μg menaquinone-7 daily for 4 wk, respectively, with a controlled diet in accordance with recommended daily intakes for 2010 in Japan. Study 2 was a double-blind, randomized placebo-controlled trial based on the results of Study 1; 120 subjects aged 20-69 y were allocated to the placebo or MK-7 group and consumed 0 or 100 μg menaquinone-7 daily for 12 wk, respectively. In both studies, circulating carboxylated osteocalcin and undercarboxylated osteocalcin were measured. The carboxylated osteocalcin/undercarboxylated osteocalcin ratio decreased significantly from baseline in the 0 μg menaquinone-7 group, in which subjects consumed the recommended daily intake of vitamin K with vitamin K1 and menaquinone-4 (Study 1). Menaquinone-7 increased the carboxylated osteocalcin/undercarboxylated osteocalcin ratio dose dependently, and significant effects were observed in both the 100 and 200 μg groups compared with the 0 μg group. Undercarboxylated osteocalcin concentrations decreased significantly, and the carboxylated osteocalcin/undercarboxylated osteocalcin ratio increased significantly in the 100 μg menaquinone-7 group compared with the placebo group (Study 2). Daily menaquinone-7 intake ≥100 μg was suggested to improve osteocalcin γ-carboxylation.