著者

Hitoshi Ogino Osamu Iida Koichi Akutsu Yoshiro Chiba Hiromitsu Hayashi Hatsue Ishibashi-Ueda Shuichiro Kaji Masaaki Kato Kimihiro Komori Hitoshi Matsuda Kenji Minatoya Hiroko Morisaki Takao Ohki Yoshikatsu Saiki Kunihiro Shigematsu Norihiko Shiiya Hideyuki Shimizu Nobuyoshi Azuma Hirooki Higami Shigeo Ichihashi Toru Iwahashi Kentaro Kamiya Takahiro Katsumata Nobuyoshi Kawaharada Yoshihisa Kinoshita Takuya Matsumoto Shinji Miyamoto Takayuki Morisaki Tetsuro Morota Kiyonori Nanto Toshiya Nishibe Kenji Okada Kazumasa Orihashi Junichi Tazaki Masanao Toma Takuro Tsukube Keiji Uchida Tatsuo Ueda Akihiko Usui Kazuo Yamanaka Haruo Yamauchi Kunihiro Yoshioka Takeshi Kimura Tetsuro Miyata Yutaka Okita Minoru Ono Yuichi Ueda on behalf of the Japanese Circulation Society the Japanese Society for Cardiovascular Surgery the Japanese Association for Thoracic Surgery and the Japanese Society for Vascular Surgery Joint Working Group

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-22-0794, (Released:2023-09-01)

参考文献数

1943

被引用文献数

13

著者

Tomoaki Iwasaki Toshiya Nishibe Yumiko Ohya Shigeru Inoue Hitoshi Ogino

出版者

The Editorial Committee of Annals of Vascular Diseases

雑誌

Annals of Vascular Diseases (ISSN:1881641X)

巻号頁・発行日

vol.11, no.1, pp.96-100, 2018-03-25 (Released:2018-03-25)

参考文献数

27

被引用文献数

5

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Background: Recently, reduced serum levels of ω-3 polyunsaturated fatty acids (PUFAs) including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), have been focused upon as newly recognized risk factors for peripheral artery disease (PAD). The present study investigated the association between disease location and serum levels of ω-3 PUFAs in patients with PAD.Methods: We retrospectively analyzed the data of patients at Tokyo Medical University between August 2011 and November 2015. The subjects included 98 patients who were categorized into two groups: those with (n=72) and without infrainguinal lesions (n=26).Results: Univariate analysis revealed that low ankle–brachial pressure index (ABI) values, low EPA levels, low DHA levels, low triglyceride levels, and diabetes mellitus were significant risk factors for infrainguinal lesions. Multivariate analysis indicated that low ABI values [p=0.018; odds ratio, 0.043; 95% confidence interval (CI), 0.003–0.579] and low DHA levels (p=0.003; odds ratio, 0.986; 95%CI, 0.977–0.995) were significant independent risk factors for infrainguinal lesions.Conclusion: Our study demonstrated that reduced serum level of DHA may underlie the presence of infrainguinal lesions in patients with PAD.