- 著者
- Hirofumi Ohashi Tomoaki Nawano Hiroaki Takashima Hirohiko Ando Reiji Goto Akihiro Suzuki Shinichiro Sakurai Wataru Suzuki Yusuke Nakano Hiroaki Sawada Masanobu Fujimoto Koshiro Sakai Yasushi Suzuki Katsuhisa Waseda Tetsuya Amano
- 出版者
- The Japanese Circulation Society
- 雑誌
- Circulation Reports (ISSN:24340790)
- 巻号頁・発行日
- vol.4, no.9, pp.439-446, 2022-09-09 (Released:2022-09-09)
- 参考文献数
- 27
Background: Physiological assessments using fractional flow reserve (FFR) and resting full-cycle ratio (RFR) have been recommended for revascularization decision making. Previous studies have shown a 20% rate of discordance between FFR and RFR. In this context, the correlation between RFR and FFR in patients with renal dysfunction remains unclear. This study examined correlations between RFR and FFR according to renal function.Methods and Results: In all, 263 consecutive patients with 370 intermediate lesions were enrolled in the study. Patients were classified into 3 groups according to renal function: Group 1, estimated glomerular filtration rate (eGFR) ≥60 mL/min/1.73 m2; Group 2, 30 mL/min/1.73 m2≤eGFR<60 mL/min/1.73 m2; Group 3, eGFR <30 mL/min/1.73 m2. The discordance between FFR and RFR was assessed using known cut-off values for FFR (≤0.80) and RFR (≤0.89). Of the 370 lesions, functional significance with FFR was observed in 154 (41.6%). RFR was significantly correlated with FFR in all groups (Group 1, R2=0.62 [P<0.001]; Group 2, R2=0.67 [P<0.001]; Group 3, R2=0.46 [P<0.001]). The rate of discordance between RFR and FFR differed significantly among the 3 groups (Group 1, 18.8%; Group 2, 18.5%; Group 3, 42.9%; P=0.02).Conclusions: The diagnostic performance of RFR differed based on renal function. A better understanding of the clinical factors contributing to FFR/RFR discordance, such as renal function, may facilitate the use of these indices.
- 著者
- Yadab P. DHAKAL Wataru SUZUKI Takashi KUNUGI Shin AOI
- 出版者
- JAPAN ASSOCIATION FOR EARTHQUAKE ENGINEERING
- 雑誌
- 日本地震工学会論文集 (ISSN:18846246)
- 巻号頁・発行日
- vol.15, no.6, pp.6_91-6_111, 2015 (Released:2015-11-25)
- 参考文献数
- 37
- 被引用文献数
- 7 7
We constructed ground motion prediction equation (GMPE) for absolute velocity response spectra in the period range of 1 to 10 s with the primary aim of providing early warning of long-period ground motions in Japan during moderate to large magnitude earthquakes. We found that the spatial variability of the observed long-period intensities can be reproduced in broad areas within a difference of one intensity by using the methodology proposed in this study that requires the magnitude and distance to be determined promptly.