- 著者
- MITOSHI AKIYAMA YOICHIRO KUSUNOKI SEISHI KYOIZUMI
- 出版者
- Journal of Radiation Research 編集委員会
- 雑誌
- Journal of Radiation Research (ISSN:04493060)
- 巻号頁・発行日
- vol.32, no.SUPPLEMENT, pp.301-309, 1991 (Released:2006-05-31)
- 参考文献数
- 38
- 被引用文献数
- 3 3
Among the peripheral blood lymphocytes, T-cells and B-cells significantly decreased in number with age. Radiation exposure resulted in further significant decrease of T-cell count (but not B cells) in the elderly. T-cell response to PHA and allo-antigens also decreased with dose in the elderly group. In contrast, NK cell number and function increased with age while a significant dose effect was not observed.