著者

MITOSHI AKIYAMA YOICHIRO KUSUNOKI SEISHI KYOIZUMI

出版者

Journal of Radiation Research 編集委員会

雑誌

Journal of Radiation Research (ISSN:04493060)

巻号頁・発行日

vol.32, no.SUPPLEMENT, pp.301-309, 1991 (Released:2006-05-31)

参考文献数

38

被引用文献数

3 3

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Among the peripheral blood lymphocytes, T-cells and B-cells significantly decreased in number with age. Radiation exposure resulted in further significant decrease of T-cell count (but not B cells) in the elderly. T-cell response to PHA and allo-antigens also decreased with dose in the elderly group. In contrast, NK cell number and function increased with age while a significant dose effect was not observed.