- 著者
- Xi ZHANG Yanan ZHANG Tao GAO Yong FANG Ting CHEN
- 出版者
- The Institute of Electronics, Information and Communication Engineers
- 雑誌
- IEICE TRANSACTIONS on Information and Systems (ISSN:09168532)
- 巻号頁・発行日
- vol.E106-D, no.5, pp.625-634, 2023-05-01
- 被引用文献数
- 1
The original single-shot multibox detector (SSD) algorithm has good detection accuracy and speed for regular object recognition. However, the SSD is not suitable for detecting small objects for two reasons: 1) the relationships among different feature layers with various scales are not considered, 2) the predicted results are solely determined by several independent feature layers. To enhance its detection capability for small objects, this study proposes an improved SSD-based algorithm called proportional channels' fusion SSD (PCF-SSD). Three enhancements are provided by this novel PCF-SSD algorithm. First, a fusion feature pyramid model is proposed by concatenating channels of certain key feature layers in a given proportion for object detection. Second, the default box sizes are adjusted properly for small object detection. Third, an improved loss function is suggested to train the above-proposed fusion model, which can further improve object detection performance. A series of experiments are conducted on the public database Pascal VOC to validate the PCF-SSD. On comparing with the original SSD algorithm, our algorithm improves the mean average precision and detection accuracy for small objects by 3.3% and 3.9%, respectively, with a detection speed of 40FPS. Furthermore, the proposed PCF-SSD can achieve a better balance of detection accuracy and efficiency than the original SSD algorithm, as demonstrated by a series of experimental results.
- 著者
- Liangzhen Gu Yanan Zhang Shuang Zhang Haijun Zhao Yuan Wang Dongfang Kan Yimin Zhang Liangqing Guo Jiajian Lv Qian Hao Xu Tian Changhong Liu ShiJun Wang Xiaochun Han
- 出版者
- Japan Oil Chemists' Society
- 雑誌
- Journal of Oleo Science (ISSN:13458957)
- 巻号頁・発行日
- vol.70, no.5, pp.685-696, 2021 (Released:2021-05-01)
- 参考文献数
- 41
- 被引用文献数
- 8
The lipid metabolism disorder is the key role of Nonalcoholic fatty liver disease (NAFLD). Selenoprotein P plays an important role in the pathological process of lipid accumulation. Coix lacryma-jboi seed oil (CLSO) is an active component extracted from Coix lacryma-jobi seed (CLS) which has been found to be effective of reducing blood fat and antioxidative. But the effect and mechanism of CLSO on NAFLD are not clear. The aim of this study was to explore the therapeutic effect and mechanism of CLSO in the treatment of NAFLD. Our result showed that CLSO decreased the liver/body weight ratio, lowered the total cholesterol (TC) and triacylglycerol (TG), and elevated the high density lipoprotein (HDL) in serum. CLSO reduced the lipid deposition in the liver of NAFLD rats. In addition, CLSO could bring down the abnormal expression of superoxide dismutase (SOD) and malondialdehyde (MDA). Moreover, CLSO significantly declined the liver apolipoprotein E (apoE), apolipoprotein E receptor (apoER) and selenoprotein P 1 (SePP1) expression. In vivo, CLSO decreased the lipid droplets and TG level, reduced the protein expression of SePP1, apoER, phosphor-adenosine 5′-monophosphate (AMP)-activated protein kinase (p-AMPK) in the cytoplasm of HepG2 cells induced by oleic acid and palmitic acid (OP). At the same time, lipid accumulation was observed in the Sepp1 high expression cells induced by endoplasmic reticulum (ER) activator tunicamycin (Tm). CLSO could identically reduce the protein expression of SePP1, apoER, p-AMPK in the cytoplasm of HepG2 cells induced by Tm. This result not only proved the CLSO had therapeutic effect on NAFLD, but also confirmed its mechanism associated with degrading the phosphorylation of adenosine 5′-monophosphate (AMP)-activated protein kinase (AMPK) which led to the decrease of the expression SePP1/apoER2 in order to reduce lipid accumulation. The study suggests CLSO has great medicinal value in treating NAFLD besides its edibility.