著者

Yao Yang Minlan Yuan Yu Zeng Yuanjing Xie Yueyao Xu Dengbin Liao Yongmei Chen Meiru Chen Yuanyuan Qu Yao Hu Wei Zhang Huan Song

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20220290, (Released:2022-12-24)

参考文献数

45

被引用文献数

1

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PurposeTo establish a prospective hospital-based cohort, featured by detailed multidimensional data of trauma patients with active follow-ups, which can be a reliable data source for all studies focusing on the effects or underlying mechanistic pathways of environmental and biological factors on multiple interested trauma-related outcomes, particularly the incidence and trajectory of trauma-related psychopathology, in Chinese population.MethodsThe China Severe Trauma Cohort (CSTC) enrolled all traumatized individuals aged 12 to 80 years admitted to the Trauma Center of West China Hospital between 1st March 2020 and 8th July 2022. The bio-sample and detailed questionnaire data were collected at recruitment, and phone/internet follow-ups were scheduled at 1-, 3-, 6-, 12-months after the baseline. Long-term health outcomes are planned to be obtained from administrative databases through data linkage.ResultsA total of 2,500 trauma patients were enrolled (response rate=87.1%) with an average age of 46.01 years, and most of the participants were males(62.6%). The proportions of participants with blood and fecal sample collected at baseline were 93.8% and 66.3%, respectively. Upon 31st August 2022, the follow-up rate was 90.0%, 77.0%, 76.5%, and 89.0% for 1-, 3-, 6-, and 12-months follow-up, respectively. Fall/wrench (47.6%) and traffic accident (26.2%) were the top causes of current trauma. The most common psychopathology at recruitment was sleep disturbance(39.4%), followed by depression(22.6%), anxiety(18.2%), and acute stress reaction(7.8%), all of which showed recovering trajectories during the follow-up period, particularly the first 3 months after baseline.ConclusionsCSTC provides a platform with multidimensional data to study both short-term and long-term trauma-related health consequences, prompting early identification and intervention for individuals with high risk of health decline after trauma exposures.

著者

Ming-Tang CHIOU Chao-Nan LIN Cheng-Yao YANG2 Guan-Shiuan SU Chuen-Fu LIN Tsung-Chou CHANG

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.12-0044, (Released:2012-06-01)

被引用文献数

1 6

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Porcine circovirus type 2 (PCV2) is the primary causative agent of postweaning multisystemic wasting syndrome. Two major PCV2 genotypes, PCV2a and PCV2b, have been identified. To explore the prevalence of different subgroups of PCV2 in Taiwan, 37 PCV2 isolates collected during 2002–2011 were analyzed. The genotypes of the PCV2 isolates collected before 2007 belonged to either PCV2a or PCV2b. However, all of the isolates collected after 2008 were PCV2b. Most of isolates obtained since 2008 have been classified into a novel genotype within subgroup of PCV2b based on complete ORF2 sequence analysis. Moreover, analysis of the PCV2 isolates from the same pig farm but from different years revealed that the viruses shifted from a PCV2b genotype to a novel subgroup of the PCV2b genotype. Collectively, PCV2b was the dominant PCV2 genotype in Taiwan currently and that the viruses have shifted into a new emerging subgroup within the PCV2b genotype.