- 著者
-
Yoshiaki Kuriu
Akifumi Kawamura
Tadashi Uragami
Takashi Miyata
- 出版者
- (社)日本化学会
- 雑誌
- Chemistry Letters (ISSN:03667022)
- 巻号頁・発行日
- pp.140103, (Released:2014-03-01)
- 被引用文献数
-
9
We prepared lectin-imprinted hydrogel layers on surface plasmon resonance (SPR) sensor chips by atom transfer radical polymerization (ATRP). In a buffer solution with a target protein, SPR signal and binding constant of the lectin-imprinted hydrogel layer chip were much larger than those of nonimprinted hydrogel layer chip prepared without using a template lectin. By molecular imprinting with ATRP, recognition sites for the target lectin were formed within hydrogel thin layers on the SPR sensor chips. The lectin-imprinted hydrogel layer chips with recognition sites for target protein are candidates as highly sensitive sensor devices for SPR sensing system.