著者

Masayuki YABUTA Fumihiko TAKESHITA Shizuko UENO Natsuki TANAKA Takahiro YANO Keiji OE Chie NIKAIDO Ken J. ISHII Masaki IMAI Yoshihiro KAWAOKA Toru TANZAWA

出版者

Catalyst Unit

雑誌

Translational and Regulatory Sciences (ISSN:24344974)

巻号頁・発行日

vol.3, no.3, pp.118-119, 2021 (Released:2021-12-24)

参考文献数

2

著者

Seiya Yamayoshi Yoshihiro Kawaoka

出版者

National Center for Global Health and Medicine

雑誌

Global Health & Medicine (ISSN:24349186)

巻号頁・発行日

vol.2, no.1, pp.1-2, 2020-02-29 (Released:2020-03-26)

参考文献数

6

被引用文献数

2

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported at the end of 2019 in China. By the end of February 2020, the virus has spread worldwide through continuous human-to-human transmission via contact and droplet infection, demonstrating the ease with which emerging viruses disperse globally through the mass transport system. Here, we summarize our knowledge of other coronaviruses that have infected humans in comparison with SARS-CoV-2.

著者

Masayuki SHIMOJIMA Yoshihiro KAWAOKA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.12-0176, (Released:2012-06-01)

被引用文献数

9 33

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The glycoprotein (GP) of lymphocytic choriomeningitis virus (LCMV), the prototype arenavirus, is a promising envelope protein of lentiviral pseudotype vectors for gene therapy. The distribution of dystroglycan, a known receptor for LCMV, cannot explain the narrow tropism of LCMV-GP-pseudotypes. Here, we examined whether infection of LCMV-GP-pseudotypes was affected by the expression of four cell surface molecules—Axl and Tyro3 (from the TAM family) and DC-SIGN and LSECtin (from the C-type lectin family)—that are known receptors of Lassa virus, another arenavirus. All four molecules enhanced LCMV-GP-pseudotype infection of cells. These results help explain the tropism of LCMV-GP-pseudotypes and further our understanding of LCMV infection in animals.