著者

Yuan Ye Xingju Liu

出版者

Japan Brain Science society

雑誌

脳科学誌 (ISSN:13415301)

巻号頁・発行日

vol.41, pp.37-47, 2013-09-30 (Released:2017-06-01)

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CD34+ cell is attached with CD34 molecule which is a cluster of differentiation molecule presented on certain cells within the human body. The number of circulating CD34 progenitors has significantly increased in peripheral blood of brain during the fast hematopoietic recovery. CD34+cells can survive, migrate and differentiate towards astrocytes or neurons after transplantation. Moreover, they improve the neurological recovery after cerebral artery occlusion. CD34 molecule is a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of stem cells to bone marrow extracellular matrix or directly to stromal cells. This review is about the factors that lead to CD34+ cell proliferation in in-vivo or in-vitro.