- 著者
- Takuma Yamamoto Katsuhiko Yoshizawa Shin-ichi Kubo Yuko Emoto Kenji Hara Brian Waters Takahiro Umehara Takehiko Murase Kazuya Ikematsu
- 出版者
- 日本毒性病理学会
- 雑誌
- Journal of Toxicologic Pathology (ISSN:09149198)
- 巻号頁・発行日
- vol.28, no.1, pp.33-36, 2015 (Released:2015-02-24)
- 参考文献数
- 17
- 被引用文献数
- 3 34
Caffeine (1,3,7-trimethylxanthine) is a popular mild central nervous system stimulant found in the leaves, seeds and fruits of various plants and in foodstuffs such as coffee, tea, and chocolate, among others. Caffeine is widely used and is not associated with severe side effects when consumed at relatively low doses. Although rarely observed, overdoses can occur. However, only a few fatal caffeine intoxication cases have been reported in the literature. Herein, we report the pathological examination results and information on caffeine concentrations in the blood, urine and main organs in a fatal caffeine intoxication case. Even though high caffeine concentrations were found in the systemic organs, no caffeine-related pathological changes were detected.