- 著者
- Tomoyuki ONISHI Naoko HIROSE Yasuyuki OTAKE Kohki ISHIKAWA Tatsuki KASHIWAGI Kunisuke IZAWA
- 出版者
- The Japan Society for Analytical Chemistry
- 雑誌
- Analytical Sciences: X-ray Structure Analysis Online (ISSN:13482238)
- 巻号頁・発行日
- vol.20, pp.x95-x96, 2004 (Released:2005-02-18)
- 参考文献数
- 3
- 被引用文献数
- 1
Both (2S,3S)- and (2R,3S)-N-tert-butoxycarbonyl-3-amino-1-chloro-2-hydroxy-4-phenylbutane (SS- and RS-Boc-ACHPB) are important intermediates of HIV protease inhibitors. Crystals of SS-Boc-ACHPB and RS-Boc-ACHPB are monoclinic P21 and orthorhombic P212121, respectively. The aromatic ring in SS-Boc-ACHPB is placed to avoid repulsive interaction with the hydroxyl group involved in intermolecular hydrogen bonds. On the other hand, the aromatic ring in RS-Boc-ACHPB is situated away from the tert-butoxycarbonylamino group, which is involved in intermolecular hydrophobic interactions with the other aromatic rings. The mode of the intermolecular hydrogen-bonding network is very different for these diastereomers.
- 著者
- KHALAJI Aliakbar Dehno AMIRNASR Mehdi FALVELLO Larry R. SOLER Tatiana
- 出版者
- The Japan Society for Analytical Chemistry
- 雑誌
- Analytical Sciences: X-ray Structure Analysis Online (ISSN:13482238)
- 巻号頁・発行日
- vol.22, pp.X47-X48, 2006
- 被引用文献数
- 1
The title complex, [(PPh<sub>3</sub>)<sub>2</sub>Ag(<i>μ</i>-N<sub>3</sub>)<sub>2</sub>Ag(PPh<sub>3</sub>)<sub>2</sub>], has been synthesized and structurally characterized by single-crystal X-ray diffraction. The silver atoms are joined through a double <i>μ</i><sub>1,3</sub>-azido (N<sub>3</sub>) bridge. To each silver atom are also coordinated two P atoms from two triphenylphosphine molecules. The coordinated polyhedron around silver is a distorted tetrahedron.
1 0 0 0 OA Crystal Structure of Minoxidil
- 著者
- Hiroyuki AKAMA Masayuki HARAMURA Akito TANAKA Toshio AKIMOTO Noriaki HIRAYAMA
- 出版者
- (社)日本分析化学会
- 雑誌
- Analytical Sciences: X-ray Structure Analysis Online (ISSN:13482238)
- 巻号頁・発行日
- vol.20, pp.x29-x30, 2004 (Released:2005-02-18)
- 参考文献数
- 4
- 被引用文献数
- 2
The title compound, C9H15N5O, is an antialopecia agent. The crystal belongs to space group P21 with cell dimensions a = 9.3799(5) , b = 8.3319(4), c = 12.9984(7)Å and β = 90.191(3)°. The final R value is 0.092. There are two crystallographically independent molecules in an asymmetric unit. They adopt significantly different conformations. The hybridization states of the nitrogen atoms in piperidine rings are markedly different in these molecules.