著者

酒井,英二

出版者

日本生薬学会

雑誌

Natural medicines

巻号頁・発行日

vol.50, no.1, 1996-02-20

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A correlation between flavonoid glycoside contents of leaves of wild Houttuynia cordata and the amount of light in the natural habitat has been reported. In this study, the effects of light conditions on the growth and yield of the plant and on the flavonoid glycoside contents of the leaves was studied in a field in Tsukuba. The flavonoid glycoside contents of the leaves of the wild plants growing in bright and shaded places were also studied. The yield of the aerial part of plants cultivated under a shaded condition (shading rate ca. 43%) was the highest. However, the flavonoid glycoside content of leaves was the highest when the plant was cultivated without a shade (open) and decreased as the shading rate increased. In the case of wild plants, too, those growing in brighter places had higher leaf flavonoid glycoside contents and this result agreed well with the result of our present cultivation experiment in the field.

著者

諸田,隆

出版者

日本生薬学会

雑誌

Natural medicines

巻号頁・発行日

vol.49, no.4, 1995-12-20

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Roots of Tripterygium wilfordii has been long used in China for treatment of autoimmune diseases such as rheumatoid arthritis, systemic lups erythematosus (SLE) and Bechet's disease, chronic nephritis, allergic conjunctivitis and rhinitis, and asthma. However, not many studies have been made on its clinical effects. We previously isolated nine diterpenoids and 17 triterpenoids from the heartwood and bark of the plant. In the present report, we examined the inhibitory activities of these constituents on leukotrien D_4-induced smooth muscle contraction which is considered to be involved in the pathology of asthma. Seven diterpenoids and ten triterpenoids were found to be quite active in this assay.