- 著者
- Osanai Toshiya Houkin Kiyohiro Uchiyama Shinichiro Minematsu Kazuo Taguchi Akihiko Terasaka Shunsuke
- 出版者
- SAGE Publications
- 雑誌
- International journal of stroke (ISSN:17474930)
- 巻号頁・発行日
- vol.13, no.4, pp.444-448, 2018-06-01
- 被引用文献数
- 16
Rationale: MultiStem® (HLM051) is one of the promising allogenic cell products for acute ischemic stroke with strong evidence. A previous phase 2 randomized, double-blind, placebo-controlled, multicenter dose-escalation trial showed the safety of MultiStem® for acute ischemic stroke, with a time window beyond that of rt-PA and endovascular thrombectomy. We aim to obtain stronger evidence and to show the efficacy of the MultiStem® for treatment of ischemic stroke. Sample size: Estimated sample size is 220 (110 patients per group), which has 90% power at 5% significance level. Methods and design: TREASURE is a randomized, double-blind, placebo-controlled, multicenter phase 2/3 trial. The trial will be done at 31 medical centers in Japan. Patients with acute ischemic stroke including motor or speech deficit defined by a National Institution of Health Stroke Scale (NIHSS) score of 8-20 at baseline will be randomized 1:1 to receive a single intravenous infusion of MultiStem® or placebo within 18-36 h of stroke onset. Study outcomes: Primary outcome in this study is the proportion of patients with an excellent outcome at day 90 defined by the functional assessment. Trial registration: ClinicalTrials.gov (NCT02961504). Conclusion: The TREASURE trial will provide a novel treatment option and expand the therapeutic window for patients with stroke if the results are positive.
- 著者
- Schug Joanna Yuki Masaki Maddux William W.
- 出版者
- Sage Publications
- 雑誌
- Psychological Science (ISSN:09567976)
- 巻号頁・発行日
- vol.21, no.10, pp.1471-1478, 2010-10
- 被引用文献数
- 194
The current research proposes a novel explanation for previously demonstrated findings that East Asians disclose less personal information to others than do Westerners. We propose that both between- and within-culture differences in self-disclosure toward close friends may be explained by the construct of "relational mobility" - the general degree to which individuals in the society have the opportunities to form new and terminate old relationships. In Study 1, we found that cross-cultural differences (Japan vs. U.S.) in self-disclosure toward a close friend were mediated by individuals' perceptions of relational mobility. In Study 2, two separate measures of relational mobility predicted self-disclosure within a single culture (Japan), and this relationship was mediated by the motivation to strengthen interpersonal relationships. We conclude that societies and social contexts high in relational mobility (where relationships can be formed and dissolved relatively easily) produce stronger incentives for self-disclosure as a social commitment device.
- 著者
- Saiki Jun
- 出版者
- SAGE Publications
- 雑誌
- Psychological science (ISSN:14679280)
- 巻号頁・発行日
- vol.27, no.2, pp.178-190, 2016-02-09
- 被引用文献数
- 7
視覚認知において色と形の情報が統合される仕組み -位置に依存しない物体記憶の生成-. 京都大学プレスリリース. 2016-01-04.
- 著者
- Mueller Charles Nagashima Miori
- 出版者
- SAGE Publications
- 雑誌
- Social Compass (ISSN:00377686)
- 巻号頁・発行日
- vol.70, no.2, pp.263-282, 2023-05-06
Factors that currently lead Japanese men to enter and remain in the Buddhist priesthood are poorly understood. This article reports the results of a qualitative study that examines the profiles of a seminary instructor and six Shingon Buddhist priests ((sic)(sic)) at Koyasan guesthouse temples ((sic)). The data, collected from semi-structured interviews, were analyzed with ATLAS.ti using a thematic analysis approach. The study identified seven key themes related to (1) family, (2) mentoring relationships, (3) education, (4) labor, (5) spiritual practices, (6) religious doctrines and faith, and (7) the devotion of guests. For the six priests, family connections were found to play an especially critical role in initial decisions to enter the priesthood, whereas other factors chiefly contributed to sustained commitment. The results are discussed in terms of theories of 'costly signalling', ego-identity statuses, and the Japanese tendency to construct personal identity within the context of social affiliations.
- 著者
- Maddux William W. Yuki Masaki
- 出版者
- Sage Publications
- 雑誌
- Personality and Social Psychology Bulletin (ISSN:01461672)
- 巻号頁・発行日
- vol.32, no.5, pp.669-683, 2006-05
- 被引用文献数
- 99 96
Previous research has demonstrated that people from East Asian cultural backgrounds make broader, more complex causal attributions than people from Western cultural backgrounds. In the current research, the authors hypothesized that East Asians would also be aware of a broader, more complex distribution of consequences of events. Four studies assessed cultural differences in perceptions of the consequences of 1) a shot in a game of pool, 2) an area being converted into a national park, 3) a CEO firing employees, and 4) a car accident. Across all four studies, compared to participants from Western cultural backgrounds, participants from East Asian cultural backgrounds were more aware of the indirect, distal consequences of events. This pattern occurred on a variety of measures, including spontaneously generated consequences, estimations of an event’s impact on subsequent events, perceived responsibility, and predicted affective reactions. Implications for our understanding of cross-cultural psychology and social perception are discussed.