Islam Y. Elgendy
Ahmed N. Mahmoud
Akram Y. Elgendy
Gary S. Mintz
- The Japanese Circulation Society
- Circulation Journal (ISSN:13469843)
- vol.83, no.6, pp.1410-1413, 2019-05-24 (Released:2019-05-24)
Background:Randomized trials have been underpowered to determine an effect of intravascular ultrasound (IVUS) guidance on hard outcomes for drug-eluting stent (DES) implantation.Methods and Results:Randomized trials that compared IVUS guidance vs. angiographic guidance for DES implantation were included; 10 trials with 5,060 patients. IVUS guidance was associated with a lower incidence of cardiovascular death (odds ratio [OR] 0.44, 95% CI 0.26–0.75), and myocardial infarction (OR 0.55, 95% CI 0.32–0.94).Conclusions:IVUS-guidance is associated with a lower incidence of cardiovascular death and myocardial infarction in the era of DES. These findings should encourage operators to use IVUS more often.