著者

前田 将司

出版者

日本結晶学会

雑誌

日本結晶学会誌 (ISSN:03694585)

巻号頁・発行日

vol.52, no.1, pp.25-30, 2010-02-28 (Released:2011-02-25)

参考文献数

27

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Here we describe the long awaited atomic structure of the gap junction channel. The structure reveals intra-/inter- monomer interactions, which stabilize the channel structure, and intercellular interactions between two apposing hemichannels. The structure also reveals the pore structure in detail, charge distribution, pore-lining residues and so on. The novel structure, pore funnel, is found on the top of the pore and the relationship with channel gating could be inspected.