著者
Naoya Shimada Yukiko Okuda Kaisei Maeda Daisuke Umeno Shinichi Takaichi Masahiko Ikeuchi
出版者
Applied Microbiology, Molecular and Cellular Biosciences Research Foundation
雑誌
The Journal of General and Applied Microbiology (ISSN:00221260)
巻号頁・発行日
pp.2020.01.003, (Released:2020-03-25)
参考文献数
24
被引用文献数
9

Heterologous production of a useful carotenoid astaxanthin was achieved in a cyanobacterium Synechocystis sp. PCC 6803 with the aid of marine bacterial genes. Astaxanthin and its intermediates emerged at high levels, whereas β-carotene and zeaxanthin disappeared in the strain. Total carotenoid accumulation was nearly two fold compared with wild type. The astaxanthin-producing strain was capable of only growing heterotrophically, which was likely due to the absence of β-carotene. Further enhanced accumulation was pursued by gene overexpression for possible rate-limiting steps in the biosynthesis pathway.

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Astaxanthin production in a model cyanobacterium <i>Synechocystis</i> sp. PCC 6803 https://t.co/uqIvr5MUY7
元ラボの新作。僕は共著にも入っていないんですけど、これ、すごいんですよ!Fig. 2をみんな見てください!青緑色のシアノバクテリア野生株に、アスタキサンチンを大量に作らせたら、真っ赤っかになっちゃったんですよ〜〜。素敵な研究ですよね〜〜 https://t.co/7qTWGFrChz

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