著者
柴田 重信 池田 祐子
出版者
日本脂質栄養学会
雑誌
脂質栄養学 (ISSN:13434594)
巻号頁・発行日
vol.24, no.1, pp.53-60, 2015 (Released:2015-05-01)
参考文献数
29
被引用文献数
2

In mammals, the circadian clock system regulates many physiological functions such as feeding, sleep-wake behavior, hormones and metabolism. Regular feeding pattern can entrain peripheral circadian clock system, whereas circadian clock can control absorption/ metabolism of food and nutrition. Thus, the interaction between food/nutrition and circadian clock is so-called as “chrono-nutrition”. For example, a bigger meal for breakfast is effective for protection from obesity, and also for entrainment of peripheral circadian clock. Intake of high fat diet disturbed the circadian clock and this clock disturbance potentiates the obesity. Circadian clock system exists in the white adipose tissue, and clock gene such as Bmal1 controls the differentiation of adipose cells and accumulation of fat in the cells. We demonstrated that fish oil, especially tuna oil, containing rich DHA/EPA increased insulin secretion and entrained peripheral circadian clock. Talking about nutrition including lipids, the idea of “chrono-nutrition” may become important and provide new aspects of the form of nutrition action.

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@shunXnegi 俺も同じ研究室の人間がそれ関連の実験を行っているので聞きかじっている程度ですけど、この分野では柴田重信という先生が活発に研究をしているようですね 以下の論文のFig.2なんか見るとスゴく面白いですよ https://t.co/CLj7qMhVv2
消費カロリー>摂取カロリーを守れっていうのはまったくその通りだと思うけど、「夜遅くに食べても太らない」はどうだろ?不規則な食生活は代謝異常を引き起こすっていう論文はいっぱい出てくるし、逆に「夜食べると太る」っていう論文もある。 https://t.co/93bc5hKNXt https://t.co/0T5Uw5vURq

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