著者
Yoshiyuki SAKAKI
出版者
The Japan Academy
雑誌
Proceedings of the Japan Academy, Series B (ISSN:03862208)
巻号頁・発行日
vol.95, no.8, pp.441-458, 2019-10-11 (Released:2019-10-11)
参考文献数
43
被引用文献数
2 2

The Human Genome Project (HGP) is one of the most important international achievements in life sciences, to which Japanese scientists made remarkable contributions. In the early 1980s, Akiyoshi Wada pioneered the first project for the automation of DNA sequencing technology. Ken-ichi Matsubara exhibited exceptional leadership to launch the comprehensive human genome program in Japan. Hideki Kambara made a major contribution by developing a key device for high-speed DNA sequencers, which enabled scientists to construct human genome draft sequences. The RIKEN team led by Yoshiyuki Sakaki (the author) played remarkable roles in the draft sequencing and completion of chromosomes 21, 18, and 11. Additionally, the Keio University team led by Nobuyoshi Shimizu made noteworthy contributions to the completion of chromosomes 22, 21, and 8. In April 2003, the Japanese team joined the international consortium in declaring the completion of the human genome sequence. Consistent with the HGP mandate, Japan has successfully developed a wide range of ambitious genomic sciences.

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多くの方にヒトゲノム完全解読に至るまでの僕の主観的な振り返りを目に止めて頂いたようですが、日本のヒトゲノム研究をPIとして永年牽引した榊 佳之先生の総説がオープンアクセスで読めますのであまり光が当たらない日本のHGPへの貢献を知りたい方はぜひこちらを一読下さい。 https://t.co/h38Hei6sb1

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