著者

鈴木 潤

出版者

Japanese Electrophoresis Society

雑誌

生物物理化学 (ISSN:00319082)

巻号頁・発行日

vol.50, no.2, pp.67-70, 2006-06-15 (Released:2009-03-31)

参考文献数

10

被引用文献数

1 1

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The microbial environment is an essential aspect of the discussion of“genvironment and health”, due to our close coexistence with microorganisms. Furthermore, on a daily basis, bacteria cause food poisoning in humans through food intake, with as many as 90% of food poisoning cases being of bacterial origin. In addition, the Food Hygiene Law classifies etiological agents responsible for food poisoning into 16 types, many of which produce hemolytic toxins as pathogenic factors. Since these toxins are protein toxins, their properties can be determined by electrophoresis analysis. The toxin properties have also been analyzed by conducting osmotic protection and hemolysis inhibition experiments, as well as through determination of their ultrastructure and hemolytic efficiency. Hemolytic efficiency is expressed numerically as a function of streptolysin O (SLO) concentration and hemolysis level, or in other words, the concentration dependency of SLO from the lowest hemolysis level to complete hemolysis. These findings will contribute to the treatment and prevention of food poisoning.