@JohnPasalis @Z_Modular eg. Optimal control in an inventory management problem considering replenishment lead time based upon a non-diffusive stochastic differential equation
https://t.co/mrRGqXVN65
@ArmineYalnizyan @TorontoStar @aballinga Giving taxpayer money to a profitable industry is a bad plan.
Rate problems in differential calculus applied to economics
https://t.co/GyF8AlHx5K
https://t.co/nTnyubMHbx
https://t.co/mrRGqXVN65
https://t.co/v84RmHgcJt
https://t.co/QGsNiGx9uh
"However, RBC Zn level was again significantly lower in TH patients than PH patients despite of the comparable serum TSH levels in both groups when RBC Zn was evaluated in patients with serum TSH levels of less than 50 mU/L."
https://t.co/QGsNiGx9uh
"There was a positive correlation between RBC Zn and serum TSH, and the latter was clearly lower in TH patients than that in PH patients."
Erythrocyte zinc concentration as an indicator to distinguish painless thyroiditis-associated transient hypothyroidism from permanent hypothyroidism
https://t.co/QGsNiGx9uh
@KyleMcnease @Atarabio @stephbrambila used ozone dialysis.
https://t.co/al1oAVng0f
"size of these amyloid microclots, ... are typically anywhere from 1–200 µm"
Implication of NF-κB Activation on Ozone-Induced HO-1 Activation
https://t.co/0KURues3s0
https://t.co/OdcamNdMod
https://t.co/pzI9GT4aVn
@mrzphd @PJPrydderch @GeoEduOne @PutrinoLab @VirusesImmunity @Doctor_IMF Ozone dialysis worked for @stephbrambila in 3 treatments.
Implication of NF-κB Activation on Ozone-Induced HO-1 Activation
https://t.co/0KURues3s0
https://t.co/al1oAVng0f
"microclots, ... are typically anywhere from 1–200 µm"
https://t.co/OdcamNdMod
https://t.co/pzI9GT4aVn
https://t.co/LoJ2yNahMl
"Candesartan not only improved Ca2+-uptake, but also prevented PKA-phosphorylation, rendering the SR less susceptible to Ca2+-leak."
https://t.co/LoJ2yNahMl
"Chronic β-receptor-stimulation did not induce any Ca2+-leak from the SR, whereas Ca2+-leak was easily induced when oxidative stress was applied to the PKA-phosphorylated RyR2."
https://t.co/NyVcvcyqrH
"Our results therefore show novel properties of CTX, which raise the possibility that CTX works as a non-toxic therapeutic agent for preventing and repairing tissue damage."
https://t.co/NyVcvcyqrH
"Interestingly, the cytotoxicity of Fas/CD95 ligand (FasL), a cytotoxic cytokine that strongly induces apoptosis, was significantly ameliorated by pre-treatment with CTX, most likely because of the upregulation of Nrf2 and HSP70."
https://t.co/NyVcvcyqrH
"Non-toxic levels of reactive oxygen species (ROS) induced by CTX activated the Nrf2 pathway without cytotoxicity, which in turn upregulated HSP70."
https://t.co/NyVcvcyqrH
"In this study, we unexpectedly found the beneficial properties of CTX that upregulate both Nrf2 and HSP70 to the extent that stress-induced damage is ameliorated."
https://t.co/NyVcvcyqrH
"CTX exhibits broad-spectrum antimicrobial activity, and thereby, is most commonly prescribed for the treatment of infectious diseases induced by Gram-positive or Gram-negative bacteria."
https://t.co/NyVcvcyqrH
"Both NF-E2-related factor 2 (Nrf2) and heat shock protein 70 (HSP70) contribute to cellular defense to various stresses, and have emerged as candidates of therapeutic targets to improve or prevent tissue damage."
https://t.co/0KURues3s0
"These results suggest that the moderate oxidative stress by ozone initially induces NF-κB activation, and this NF-κB activation is required for HO-1 induction at the late phase of the moderate stress."
https://t.co/0KURues3s0
"Induction of NF-κB-mediated COX-2 mRNA expression was observed at the early phase after stimulation (30-60 min after ozone treatment)."
"However, induction of HO-1 mRNA expression was observed at the late phase of stimulation (6 h after stimulation)."
https://t.co/0KURues3s0
"while Nrf2 is involved in anti-inflammatory responses by controlling expression of numerous antioxidant enzymes such as heme oxygenase-1 (HO-1)."
https://t.co/0KURues3s0
"NF-κB is involved in inflammatory responses by regulating expression of cyclooxygenase-2 (COX-2) and various inflammatory cytokines"
https://t.co/0KURues3s0
"Furthermore, it has been shown that this conflict response is mainly regulated by two transcriptional factors, nuclear transcriptional factor κB (NF-κB) and nuclear factor erythroid 2-related factor 2 (Nrf2)."
Implication of NF-κB Activation on Ozone-Induced HO-1 Activation
https://t.co/0KURues3s0
"The controlled and moderate oxidative stress such as ozone induces both inflammatory and anti-inflammatory response."
https://t.co/LExO9B9brj
"Radicicol, a HSP90 inhibitor, has been reported to induce the expression of HSP70 protein."
"Administration of radicicol with quercetin, an inhibitor of HSP70 induction, eliminated the renoprotective effect of radicicol."
The Protective Effect of Radicicol Against Renal Ischemia–Reperfusion Injury in Mice
https://t.co/LExO9B9brj
"Overexpression of heat shock protein 70 kDa (HSP70) is known to confer cellular protection against ischemia–reperfusion (I/R) injury."
Retinoid therapy for autoimmune diseases
https://t.co/Nl0bqqdb6R
"In particular, Th1 dominant autoimmune diseases may be the targets of the retinoids."
https://t.co/eE7nLsGFBs https://t.co/gI5ZinKzMZ
https://t.co/KWTGZsXvpz
"Vitamin K2 is suggested to attenuate activated T-cell immunity in atopic dermatitis patients through the inhibition of mitogen-activated protein kinase-Mek1-ERK1/2 and SAPK/JNK signaling pathways."
Vitamin K2 Suppresses Proliferation and Inflammatory Cytokine Production in Mitogen-Activated Lymphocytes of Atopic Dermatitis Patients through the Inhibition of Mitogen-Activated Protein Kinases
https://t.co/KWTGZsXvpz https://t.co/10yxXEem1t
Protection of Tong-Qiao-Huo-Xue Decoction against Cerebral Ischemic Injury through Reduction Blood–Brain Barrier Permeability
https://t.co/oupDpUnd9P https://t.co/0bg2JdwM09
Shikonin Directly Inhibits Nitric Oxide Synthases: Possible Targets That Affect Thoracic Aorta Relaxation Response and Nitric Oxide Release From RAW 264.7 Macrophages
https://t.co/eQ0sn8QErp
"shikonin inhibits all isoforms of NOS (IC50s, 4 – 7 μM)"
Microvascular Angina. The Possible Role of Inflammation, Uric Acid, and Endothelial Dysfunction
https://t.co/C0sR1WWL5e
"an inflammatory element (reflected as a higher serum hsCRP level)"
"endothelial dysfunction (reflected as impaired brachial artery FMD)"
Different effect of serotonin on intracellular calcium ion dynamics in the smooth muscle cells between rat posterior ciliary artery and vorticose vein
https://t.co/Yx62bpU4lX
Cilostazol Inhibits Cytokine-Induced Tetrahydrobiopterin Biosynthesis in ... Endothelial Cells
https://t.co/8EQgOMZ6gW
"Cilostazol decreased the GTPCH activity as well as the expression of GTPCH mRNA and protein"
"cilostazol inhibited cytokine-stimulated BH4 biosynthesis"
#SARSCoV2-related Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease: A Case Report and Literature Review
https://t.co/P0B0YQd13o
"The response to immunotherapy was favorable."
@JohnPasalis With housing in Canada being a global commodity, how long does it take to build a unit of housing versus how long does it take to buy a unit of housing?
With housing being used to store money outside the banking system, can you ever build fast enough?
https://t.co/mrRGqXDDRX
Treatment of Porcine Oocytes with MEM Vitamins During In Vitro Maturation Improves Subsequent Blastocyst Development Following Nuclear Transfer
https://t.co/IcnydAXLPP
https://t.co/dQ5isE8xnN
"Alpha-ketoglutarate is a key intermediate in the Krebs cycle, and a rate-limiting cofactor of prolyl-4-hydroxylase. It also has a potent effect on increasing the proline pool during collagen production"
@SabrinaMaddeaux @TOAdamVaughan @JustinTrudeau NREL ran 100 million simulations to see how Los Angeles could transition to 100% renewable energy.
https://t.co/ScVaxajOHL
Federal government could use differential calculus to model the housing market. #cdnpoli #vanre #tore
https://t.co/mrRGqXDDRX
Nevermind: https://t.co/xUbLoXUK9l
Daily Intake of Trehalose Is Effective in the Prevention of Lifestyle-Related Diseases in Individuals with Risk Factors for Metabolic Syndrome
https://t.co/urCRlC1CyC
https://t.co/NA1yNx3Igc
"high inverse correlations were found among the percentage of LDH-4 and LDH-5 and serum vitamin C levels all of age groups"
https://t.co/2HXX5JFN1L
Effect of the Co-Administration of Vitamin C and Vitamin E on Tyrosine Hydroxylase and Nurr1 Expression in the Prenatal Rat Ventral Mesencephalon
https://t.co/SnqJQ3XhFf
@sffed You could model the problem with differential calculus but it is not necessary to understand why housing will always be unaffordable in the current system.
https://t.co/mrRGqXDDRX