著者

丸 勇史 大西 淳 山口 信也 小田 泰雄 掛樋 一晃 太田 泰弘

出版者

公益社団法人 日本食品科学工学会

雑誌

日本食品科学工学会誌 : Nippon shokuhin kagaku kogaku kaishi = Journal of the Japanese Society for Food Science and Technology (ISSN:1341027X)

巻号頁・発行日

vol.48, no.2, pp.146-149, 2001-02-15

参考文献数

7

被引用文献数

1 6

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We examined an estrogen-like activity in the pomegranate (<I>Punica granatum</I>) juice. The juice or its methanol eluate from C18 cartridge competed with 17&beta;-estradiol for estrogen receptor (ER) binding and also stimulated proliferation of human ER-positive cell (MCF-7) <I>in vitro</I>. Furthermore, they effectively increased uterine weight in the ovariectomized rat. On the basis of these data, we concluded that the pomegranate juice contained estrogen-like compounds.