著者

和田 啓爾 石垣 静香 上田 かおり 阪田 正勝 羽賀 正信

出版者

公益社団法人日本薬学会

雑誌

Chem Pharm Bull. (ISSN:00092363)

巻号頁・発行日

vol.33, pp.3555-3557, 1985

被引用文献数

2

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An antivitamin B_6,4'-methoxypyridoxine (1) was isolated from the seed of Ginkgo biloba L. (Ginkgoaceae). The albumen of the seed of G. biloba L., which is called "Gin-nan or Ginkyo", is used as a crude drug in China and as food in Japan. However, in Japan, there have been about 70 reports of "Gin-nan sitotoxism." In this paper, we report that the substance responsible for this sitotoxism is 4'-methoxypyridoxine (1), which is known to have antivitamin B_6 activities. This compound (1) is reported for the first time from natural products.