- 著者
-
味澤 幸義
赤羽 健司
赤羽 増夫
佐藤 和明
玉井 哲郎
斉藤 勝
田中 信之
鎌田 晃爾
小林 通洋
- 出版者
- 公益社団法人日本薬学会
- 雑誌
- 藥學雜誌 = Journal of the Pharmaceutical Society of Japan (ISSN:00316903)
- 巻号頁・発行日
- vol.116, no.9, pp.735-747, 1996-09-25
- 参考文献数
- 13
A number of benzimidazole derivatives were synthesized and tested for cholecystokinin A (CCK-A) receptor inhibitory activity in order to study structure-activity relationships. Significant CCK-A receptor inhibitory activities were found in the compounds having carboxyl or tetrazolyl group. As the most preferred compound, 4-(5,6-dichlorobenzimidazol-2-yl)-N-(3-methoxypropyl)-N-pentylglutaramic acid (4g) was selected.