著者

井上 隆夫 石館 八重子 藤田 正雄 久保 正良 福島 美雪 永井 正博

出版者

公益社団法人日本薬学会

雑誌

藥學雜誌 (ISSN:00316903)

巻号頁・発行日

vol.98, no.1, pp.41-46, 1978-01-25

被引用文献数

1

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Chemical constituents of the leaves and stem bark of Acer nikoense MAXIM. (Aceraceae) were examined. β-Amyrin, β-sitosterol contaminated with campesterol and stigmasterol, and β-sitosterol glucoside were obtained from both parts of the plant. β-Amyrin acetate, quercetin, quercitrin, and ellagic acid were isolated from the leaves, and scopoletin, (+)-rhododendrol (VIII), (+)-catechin, and two new glycosides named aceroside I (XI), C_<25>H_<32>O_8,mp 170-171° (from acetone), [α] D-7.7°, and epi-rhododendrin (XII), C_<16>H_<24>O_7,mp 81-84°, [α] D -15.5°, from the stem bark. The absolute configuration of VIII was proposed to be S from empirical rule on optical rotation-chirality relationship. Hydrolysis of aceroside I (XI) afforded acerogenin A (XIII) as its aglycone, whose structure has already been reported. The structure of epi-rhododendrin (XII) was elucidated to be (S)-4-(p-hydroxyphenyl) butan-2-ol 2-β-D-glucopyranoside from chemical and spectral evidences.