著者

倉林 工

出版者

新潟大学

雑誌

新潟医学会雑誌 (ISSN:00290440)

巻号頁・発行日

vol.116, no.9, pp.418-422, 2002-09-10

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The premenstrual syndrome (PMS) is a collection of affective, behavioral, and somatic disorders that usually occurs in the last 7 to 10 days of the cycle. The most frequently encountered symptoms include abdominal bloating, anxiety or tension, breast tenderness, depression, fatigue, lack of energy, unprovoked anger or irritability, difficulty concentrating, thirst and appetite changes, and variable degrees of edema of the extremities. The etiology of PMS is still not well understood. Selective serotonin reuptake inhibitor (SSRI) is effective for the psychological symptoms of PMS. Perimenopausal estrogen loss causes the various climacteric disorders including vasomotor symptoms, atrophic changes, psychophysiologic effects. Climacteric disorders was caused by not only hypoestrogenemia but also social and psychologrcal factors. Hormone replacement therapy is one of the effective treatments for vasomotor symptoms of climacteric disorders.