著者

Namba Tsuneo HATTORI MASAO TSUNEZUKA MASA YAMAGISHI TAKAYOSHI KONISHI KENICHI

出版者

日本生薬学会

雑誌

生薬学雑誌 (ISSN:00374377)

巻号頁・発行日

vol.36, no.3, pp.222-227, 1982-09-20

被引用文献数

1

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By the agar dilution technique, magnolol and honokiol, the components of Magnoliae Cortex, were demonstrated to have antibacterial activity against various strains of gram-positive bacteria, including Streptococcus sp., Staphylococcus sp., Peptococcus sp., Peptostreptococcus sp., Micrococcus sp., Lactobacillus sp., Eubacterium sp., Bifidobacterium sp. and Clostridium sp. with minimal inhibitory concentrations of 12. 5-25 μg/ml, but not against those of gram-negative bacteria. Both compounds were strongly bactericidal against Streptococcus mutans, Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus etc., which were killed within 2. 5 mins in contact with the solutions of 100μg/ml.