著者

横田 万之助

出版者

一般社団法人 日本感染症学会

雑誌

感染症学雑誌 (ISSN:03875911)

巻号頁・発行日

vol.44, no.7, pp.388-394, 1970

被引用文献数

1

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Suppositorium, a form of medication, has already been brought into use since old egyptyan andancient chinese era, chiefly for local use. But, practically, it was since 17th century thatsuppositorium became gradually one of usual forms of medication. In Japan, however, it is not so favourable type of drugs, as compared in the countries in Europe or America. But recently, it has become used more widely for systemic purpose to avoid some untoward gastric side effects due to drugs. Thus, I had an oppotunity to administer Erythrosin-suppositorium, newly made and delivered to us, to the patients thought to have bacterial infections. In all, 18 patients were treated as shown in Table 1. They were: 1 c.c.+otitis media, 1 chronic upper respiratory inflamation, 1 pyelitis, 1 bronchopneumonia, 1 alveolar pyorrhea, 4 scarlatina and 9 angina tonsillaris.<BR>All were well tolerated and cured except one with chronic upper respiratory inflamation. These results were thought to be same, as compared with hitherto known results of usual perioral Erythrosin tablet. Moreover, this Erythrosin-suppositorium was well tolerated without any gastric disorder in 2 patients in this series, who always complained of some gastric disorders after oral Erythrosin-tablet. There was no side-effect seen in this series. It was noticed that in some younger children, the relation between their normal defecation time and drug-administration time schould be taken in care, because their anal mucosa becomes a little irritated shortly after insertion of suppository. A new method for evaluation of drug with anti-streptococcal activity was described and shown in coloured figures.