著者

木野 孔司 片岡 弘一 塩田 重利 鄭 勲 仲井 義信 和気 裕之 泉 祐幸 大村 欣章 鹿島 健司 渋谷 寿久 折原 二郎

出版者

特定非営利活動法人 日本口腔科学会

雑誌

日本口腔科学会雑誌 (ISSN:00290297)

巻号頁・発行日

vol.37, no.1, pp.242-263, 1988

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Tendernesses and mouth opening pains at the region of temporomandibular joints and/or in masticatory muscles are very common on temporomandibular joint disorder patients.<BR>We usually give these patients anti-inframmatory analgesics or muscle relaxants until the treatment plan is decided, or when the splint therapy is ineffective for removing the tenderness or pain.<BR>Recently we have had an opportunity to use a new anti-inframmatory analgesic of arylacetate derivatives, Amfenac Sodium (AMF) to the patients who have temporomandibular joint disorders, and have evaluated the analgesic efficacy, side effect and usefulness of this analgesic.<BR>27 patients aged from 16 to 71 years (severity: mild 11, moderate 14 and severe 2) were given AFM (200 mg/day for 14 days) and evaluated symptoms were spontaneous pain, tenderness, mouth opening pain, interincisal opening range, clickin sound and crepitus at the 7th day and at the 14th day.<BR>As a result, total improvements were as follows: excellent 4 (14.8%), moderate 13 (48.1%), little 9 (33.3%), no change 1 (3.7%).<BR>6 side effects (22.2%) were reported, but those were mild (5 cases), or moderate (1 case). No severe side effect was found.<BR>Consequently, we concluded the usefulness of AMF as followed: very useful 4 (14.8%), luseful 12 (44.4%), relatively useful 10 (37.0%). Total usefulness including very useful, useful and relatively useful was 96.2%.