著者

深野 義人 宮澤 由妃 見越 大樹 井上 寿男 丸岡 秀一郎 黒田 和道 権 寧博 橋本 修 山岸 賢司

出版者

Society of Computer Chemistry, Japan

雑誌

Journal of Computer Chemistry, Japan (ISSN:13471767)

巻号頁・発行日

vol.13, no.6, pp.332-334, 2015

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To establish a system for the early diagnosis of respiratory diseases, we developed a method for analyzing RNA sequence data obtained by next-generation sequencer identify genes showing altered expression as biomarkers of respiratory tract infection. The respiratory tracts of mice were exposed to lipopolysaccharide to establish a model of respiratory disease. Twenty-five genes exhibited significantly altered RNA expression following exposure. We identified non-coding RNAs in five regions that could be candidate biomarkers of respiratory diseases.