著者

田辺 良久

出版者

公益社団法人 日本薬学会

雑誌

藥學雜誌 (ISSN:00316903)

巻号頁・発行日

vol.74, no.2, pp.162-167, 1954

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Syntheses of the Brooker-type dyes were reported in Part XV and XVI of this series, but some counter-argument has been made against the conclusion of the Brooker-type structure because of the difficulty of the mutual reaction of negative anilino groups and the possibility of another substitution in this synthetic method. The conclusion of the Brooker-type dyes was made from the analytical values and absorption spectra but further proof of the formation of a Brooker-type dye by the substitution of an anilino group in the <i>meso</i>-position was affored by the application of &omega;-phenylaminovinylbenzothiazolium ethiodide or &omega;-phenylamino-7-methylbenzothiazolium ethiodide on binuclear trimethinethiocyanine dye possessing inactive methyl in the terminal group and anilino group in the <i>meso</i>-position, to a Brooker-type thiocyanine with a terminal methyl, whose absorption spectrum was similar to or the same as that of binuclear trimethine dyes. It was also experimentally proved that reaction of negative anilino groups does occur by the fact that 1, 1&prime;-diethyl-2, 2&prime;-trimethinethiocyanine iodide was obtained from &omega;-phenylaminovinyl-benzothiazolium ethiodide and benzothiazole-2-aldehyde <i>p</i>-dimethylaminoanil ethiodide.