著者
渡辺 正純 豊田 満里子 今田 伊助 森本 浩
出版者
公益社団法人日本薬学会
雑誌
Chemical & pharmaceutical bulletin (ISSN:00092363)
巻号頁・発行日
vol.22, no.1, pp.176-182, 1974-01-25
被引用文献数
1

Urinary metabolites from rabbits dosed with phylloquinone and dl-α-tocopheryl acetate were examined. We found that phylloquinone was excreted as conjugate forms of 2-methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone and 2-methyl-3-(3'-carboxybutyl)-1,4-naphthoquinone, and dl-α-tocopheryl acetate was excreted mainly as the conjugate form of 2,3,5-trimethyl-6-(5'-carboxy-3'-hydroxy-3'-methylpentyl)-1,4-benzoquinone lactone and in small amounts, as the conjugate form of 2,3,5-trimethyl-6-(3'-carboxybutyl)-1,4-benzoquinone.