- 著者
-
渡辺 正純
豊田 満里子
今田 伊助
森本 浩
- 出版者
- 公益社団法人日本薬学会
- 雑誌
- Chemical & pharmaceutical bulletin (ISSN:00092363)
- 巻号頁・発行日
- vol.22, no.1, pp.176-182, 1974-01-25
- 被引用文献数
-
1
Urinary metabolites from rabbits dosed with phylloquinone and dl-α-tocopheryl acetate were examined. We found that phylloquinone was excreted as conjugate forms of 2-methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone and 2-methyl-3-(3'-carboxybutyl)-1,4-naphthoquinone, and dl-α-tocopheryl acetate was excreted mainly as the conjugate form of 2,3,5-trimethyl-6-(5'-carboxy-3'-hydroxy-3'-methylpentyl)-1,4-benzoquinone lactone and in small amounts, as the conjugate form of 2,3,5-trimethyl-6-(3'-carboxybutyl)-1,4-benzoquinone.