著者

佐保 辰典

出版者

医用画像情報学会

雑誌

医用画像情報学会雑誌 (ISSN:09101543)

巻号頁・発行日

vol.31, no.2, pp.xxxvi-xxxviii, 2014 (Released:2014-08-26)

参考文献数

13

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The Arterial disease caused by lifestyle, and mortality is 30% or more. Atherosclerosis is contributed not only medical factor, but also the stress by hemodynamics. The aim of this study was to evaluate the impact of stress in the carotid artery using computed fluid dynamics analysis. We made computational fluid dynamics analysis system by open sourse softwear. And we evaluated stress and flow velocity using a carotid artery model that was based MRA images. The carotid bifurcation analysis model showed a voltex flow and a decrease in flow velocity in the carotid bulb area. The finding results suggested that hemodynamics contributes to the atherosclerosis.

著者

佐保 辰典 大西 英雄

出版者

公益社団法人 日本放射線技術学会

雑誌

日本放射線技術学会雑誌 (ISSN:03694305)

巻号頁・発行日

vol.71, no.12, pp.1157-1164, 2015 (Released:2015-12-20)

参考文献数

31

被引用文献数

1 3

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Purpose: Detailed strategy for regional hemodynamics is significant for knowledge of plaque development on vascular diseases such as atherosclerosis. The aim of this study was to derive relation between atherosclerosis and hemodynamics at human carotid bifurcation by the use of computational fluid dynamics (CFD), and to provide more accurate hemodynamic information. Methods: Blood velocity datasets at common carotid artery were obtained by phase-contrast cine magnetic resonance imaging (PC cine MRI). Carotid bifurcation model was computed for systolic, mid-diastolic, and end-diastolic phase. Comparison of wall shear stress (WSS) was performed for each cardiac phase. Results: PC cine MRI provided velocity measurement for common carotid artery with various cardiac phases. The blood velocity had acute variation from 0.21 m/s to 1.07 m/s at systolic phase. The variation of WSS during cardiac phase was presented at carotid bifurcation model. High shear stress area was observed at dividing wall for all cardiac phases. The systole-diastole WSS ratio was 10.15 at internal carotid side of bifurcation. And low shear stress (<0.5 Pa) was observed at internal carotid side of bifurcation. Conclusion: Bifurcation area represented low shear stress and changed significantly WSS. The specific area with significant change in shear stress and low shear stress had good agreement with predilection sites of atherosclerosis. The result suggested that hemodynamics was related to atherosclerosis, and CFD analysis with various cardiac phases that were provided by PC cine MRI was allowed to determine an accurate analysis condition. This led to the representation of hemodynamics in vivo.