著者

則武 正基 神谷 博昭 横井 基夫

出版者

JAPANESE SOCIETY OF ORAL THERAPEUTICS AND PHARMACOLOGY

雑誌

歯科薬物療法 (ISSN:02881012)

巻号頁・発行日

vol.20, no.3, pp.125-129, 2001-12-01 (Released:2010-06-08)

参考文献数

20

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We often worry about oral lichen planus (OLP) with chronic inflammation, which is an intractable disease in the treatment. A study was carried out to evaluate the efficacy of allopurinol mouthwash (ALP) on OLP.We studied 9 cases (1 male and 8 females) of OLP that were clinically diagnosed in our ambulatory practice during the period from July 1996 to July 1997. The average age was 58.7, ranging from 23 to 82 years. The effect measurement was carried out after 4 weeks of administration, and there were 3 complete responses, 4 partial responses, and 2 minor responses.ALP was reported to be effective for prevention and treatment of the stomatitis, which develops during cancer chemotherapy. ALP can be easily used by gargling only, and no side effects were seen, so it seemed to be a useful drug.