著者

平井 照久

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.47, no.5, pp.317-322, 2007 (Released:2007-09-28)

参考文献数

21

被引用文献数

1 1

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Major facilitator superfamily (MFS) is the largest family of secondary transporters. MFS includes uniporter, antiporter and symporter. The structure of oxalate transporter reported by electron crystallography showed a “closed” conformation and it revealed remarkably symmetric architecture with twelve helices surrounding a central cavity. Some of the structures reported by X-ray crystallography showed “open” conformation. Comparing these structures, a transport mechanism based on the simple domain movement has been proposed.