10 0 0 0 OA 群集事故災害予防に関するバイオメカニクス研究のアプローチ
- 著者
- 望月 康廣 鈴木 基継 西本 哲也 本村 友一 宇治橋 貞幸
- 出版者
- 一般社団法人 日本機械学会
- 雑誌
- 公開研究会・講演会技術と社会の関連を巡って : 技術史から経営戦略まで : 講演論文集 2016 (ISSN:24329487)
- 巻号頁・発行日
- pp.324, 2016 (Released:2017-06-19)
2 0 0 0 OA 脳組織染色による脳実質の圧縮ひずみと細胞損傷の関係
- 著者
- 西本 哲也 望月 康廣
- 出版者
- 一般社団法人 日本機械学会
- 雑誌
- 日本機械学会論文集 (ISSN:21879761)
- 巻号頁・発行日
- pp.13-00729, (Released:2015-01-14)
- 参考文献数
- 26
- 被引用文献数
- 1
The aim of this study was to examine micro injuries of brain tissue to gain a better understanding of head injury tolerance. Compression stress relaxation experiments were conducted in vitro, using porcine brain tissue and subsequently analysed using two stain methods; immunofluorescent stain and immunoenzymatic stain. In these in vitro stress relaxation experiments, brain specimens were compressed quasi-statically at 1 mm/s, for compression strains ranging from 10% to 50%, in ten percent increments. Using the immunofluorescent stain method, it was observed that axon tear occurred at a compression strain of 30% or greater. The distribution of the damage ratio of the transverse length to the longitudinal length of brain nerve cells (referred to as an aspect ratio) using immunoenzymatic stain method in the brain tissue under loading was also examined. This indicated that at a compression strain of 30% or greater the aspect ratio exceeded 2.0. The results of this study show that a compression strain of 30% corresponds to the threshold for the extreme aspect ratio of 2.0; where the transverse length of deformed nerve cell is two times greater than longitudinal length.