- 九州齒科學會雜誌 : Kyushu-Shika-Gakkai-zasshi (ISSN:03686833)
- vol.51, no.5, pp.699-704, 1997-10-25
The region of the mid-dorsum of the tongue is the preferred site of Median Rhomboid Glossitis (M. R. G.). At present, two theories, a developmental anomaly and inflammatory reaction, are mainly mentioned concerning the etiology of the M. R. G., whereas the absolute cause is unclear. There were four thousand cases in Kyushu Dental College Hospital from 1987 to 1996, but only three cases were diagnosed as M. R. G.. Histologically, Candida hyphae existed in the parakeratinized layer and lymphoplasmacytic infiltration was present in the lamina propria. These findings demonstrated that the etiology of the M. R. G. is a localized chronic Candida infection, not only a developmental anomaly.