著者

栗原 悟

出版者

相模女子大学

雑誌

人間社会研究 (ISSN:13494953)

巻号頁・発行日

vol.12, pp.89-108, 2015-03

著者

小嶋 正治 栗原 悟 金沢 洋子 原田平 輝志 前原 喜彦 遠藤 英也

出版者

The Pharmaceutical Society of Japan

雑誌

Chemical and Pharmaceutical Bulletin (ISSN:00092363)

巻号頁・発行日

vol.36, no.3, pp.1194-1197, 1988-03-25 (Released:2008-03-31)

参考文献数

16

被引用文献数

8 11

---

The metabolic products of 2-deoxy-2-fluoro-D-glucose (FDG) and 2-deoxy-2-fluoro-D-mannose (FDM) in sarcoma 180 cells transplanted in mice were investigated by fluorin-19 nuclear magnetic resonance (19F-NMR) spectroscopy. It became apparent that the administered FDG was converted to FDM (and/or FDM-6-phosphate) in tumor cells, and also the administered FDM was converted to FDG (and/or FDG-6-phosphate). At 9h after administration of FDM, the ratio of FDG (and/or FDG-6-phosphate) and FDM (and/or FDM-6-phosphate) reached equilibrium. On the other hand, it took more than 48h in the case of FDG administration. The equilibrium amount of FDM (and/or FDM-6-phosphate) was approximately four times as much as that of FDG (and/or FDG-6-phosphate) in both cases.

著者

栗原 悟

出版者

相模女子大学

雑誌

人間社会研究 (ISSN:13494953)

巻号頁・発行日

vol.12, pp.89-108, 2015-03