著者

橋本 喜輝 深澤 啓二郎 藤井 恵美 高安 定 阪上 雅史

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.98, no.2, pp.131-135, 2005-02-01

参考文献数

10

被引用文献数

2 1

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We reviewed three cases (0.52%) of congenital anosmia without hypogonadism. None of the three cases demonstrated any response to the intravenous olfactory test, or to T & T olfactometry. Each olfactory cleft was normal with endoscopy. Biopsy of mucosa of the olfactory cleft in one of three cases showed that olfactory mucosa could not be detected in the mucosal specimen and that only respiratory mucosa was identified. Hypoplasia or lack of olfactory bulbs and sulci olfactorius was demonstrated on brain MRI in all cases, supporting a diagnosis of congenital anosmia. MRI was useful for the diagnosis of congenital anosmia without hypogonadotropic hypogonadism.