著者

織部 元廣 永野 修司 立川 裕史 塚川 博志

出版者

一般社団法人 日本臨床リウマチ学会

雑誌

臨床リウマチ (ISSN:09148760)

巻号頁・発行日

vol.19, no.1, pp.24-30, 2007-03-30 (Released:2016-12-30)

参考文献数

25

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We evaluated the effects of fasting on symptoms in 15 fibromyalgia syndrome (FMS) patients and 6 rheumatoid arthritis (RA) patients over 10 days in an open, non-randomized, controlled study. The results revealed significantly greater improvement (p<0.05) in the visual analogue scale (VAS) of pain in the 13 out of 15 FMS patients who completed the fasting versus the 6 RA patients in the10 days duration. Both groups reduced in body weight with a significant average loss of 5 kg (p<0.01) respectively. The appearance of Ketone bodies in urine did not seem to affect the level of pain reduction. Obviously, the VAS score of the RA group showed a different pattern in the10days duration compared to the FMS group. The RA group showed a relatively “straight line pattern”. That is within the10 days, relatively insignificant fluctuation in the VAS was observed within the entire group. On the other hand, almost every one in the FMS group showed a “fluctuated line pattern” of aggravation, and after that the VAS score rapidly decreased. As a marked decrease in the VAS score occurred when starvation appeared, it suggested the sensation of starvation played an important role in the disappearance of bodily pains with the FMS group. It is therefore concluded that fasting therapy has a beneficial effect on FMS symptoms, as compared to the insignificant effect on RA symptoms, at least in a short period such as 10 days.

著者

織部 元廣 永野 修司 立川 裕史 塚川 博志

出版者

一般社団法人 日本臨床リウマチ学会

雑誌

臨床リウマチ (ISSN:09148760)

巻号頁・発行日

vol.19, no.1, pp.24-30, 2007

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&nbsp;&nbsp;&nbsp;&nbsp;We evaluated the effects of fasting on symptoms in 15 fibromyalgia syndrome (FMS) patients and 6 rheumatoid arthritis (RA) patients over 10 days in an open, non-randomized, controlled study. The results revealed significantly greater improvement (p<0.05) in the visual analogue scale (VAS) of pain in the 13 out of 15 FMS patients who completed the fasting versus the 6 RA patients in the10 days duration.<br>&nbsp;&nbsp;&nbsp;&nbsp;Both groups reduced in body weight with a significant average loss of 5 kg (p<0.01) respectively. The appearance of Ketone bodies in urine did not seem to affect the level of pain reduction. Obviously, the VAS score of the RA group showed a different pattern in the10days duration compared to the FMS group.<br>&nbsp;&nbsp;&nbsp;&nbsp;The RA group showed a relatively "straight line pattern". That is within the10 days, relatively insignificant fluctuation in the VAS was observed within the entire group. On the other hand, almost every one in the FMS group showed a "fluctuated line pattern" of aggravation, and after that the VAS score rapidly decreased. As a marked decrease in the VAS score occurred when starvation appeared, it suggested the sensation of starvation played an important role in the disappearance of bodily pains with the FMS group.<br>&nbsp;&nbsp;&nbsp;&nbsp;It is therefore concluded that fasting therapy has a beneficial effect on FMS symptoms, as compared to the insignificant effect on RA symptoms, at least in a short period such as 10 days.

著者

岡本 和彦 梅野 守男 高木 宏治 永野 修司 武田 誉久

出版者

The Japanese Society of Internal Medicine

雑誌

日本内科学会雑誌 (ISSN:00215384)

巻号頁・発行日

vol.87, no.4, pp.727-729, 1998-04-10

参考文献数

8

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症例は69歳の女性患者. 55歳よりうつ病と診断され,トリプタノール^®(amitryptyline) 20mg/day,アモキサン^®(amoxapine) 25~75mg/dayを内服していた.平成8年8月6日,起床時から意識障害,発熱,筋強直,頻拍,発汗が出現したため,当院に入院となった.入院時の血液検査では白血球増加, CPKの上昇を認め,抗うつ薬の服用歴と臨床症状および検査成績より悪性症候群を疑い,抗うつ薬投与を中止した.しかし,第2病日目より呼吸不全,血小板減少, FDP上昇を呈し, DICの併発を考えた.これらに対して,ソルメドロール^®(methylprednisolone sodium succinate)とFOY^®(gabexate mesilate)の投与を行い経過は良好であった.我々は,長期にわたり少量の抗うつ薬の内服中に,明らかな誘因もなく悪性症候群を発症し呼吸不全, DICを併発し救命しえた稀な症例を経験したので報告した.