- 著者
- 片岡 裕美 村松 泰余 福井 貞夫 峯 孝則 西川 淳一 扇間 昌規
- 出版者
- 日本食品化学学会
- 雑誌
- 日本食品化学学会誌 (ISSN:13412094)
- 巻号頁・発行日
- vol.19, no.1, pp.49-53, 2012-04-23 (Released:2017-01-27)
- 参考文献数
- 6
The water level of PET bottle mineral waters sold on hot summer days seem to vary. This led us to simulate the high temperature condition (37℃) and examine the change in the quantity and quality of natural mineral water in unopened PET bottles. The results showed that approximately 1 g of water was lost per week when the bottle was kept unopened at 37℃. There was also a change in quality, due to precipitation of calcium carbonate, decline of hardness, and decrease of pH.
1 0 0 0 骨粗鬆症治療におけるビタミンD製剤と生薬製剤併用リスク評価
- 著者
- 高岡 彩子 梅野 耀弘 城戸 克己 廣村 信 片岡 裕美 飯田 浩子 田鶴谷(村山) 惠子
- 雑誌
- 日本薬学会第142年会(名古屋)
- 巻号頁・発行日
- 2022-02-01
1 0 0 0 食品による生薬製剤のマスキング効果
- 著者
- 城戸 克己 廣瀬 恵美 片岡 裕美 増田 寿伸 田鶴谷(村山) 惠子
- 出版者
- 日本食品化学学会
- 雑誌
- 日本食品化学学会誌 (ISSN:13412094)
- 巻号頁・発行日
- vol.26, no.1, pp.68-76, 2019 (Released:2019-04-26)
- 参考文献数
- 18
Many crude drug products elicit a bitter taste, because there are a variety of bitter components in them. However, there are no good methods of masking their bitter taste. Therefore, new masking methods are widely required. As a general method to administer crude drug products to patients, they are dissolved in hot water or mixed in food or juice. However, there is a risk that patients may not want to eat the food if the crude drug products alter the taste of the food. In this study, we conducted a sensory evaluation including a questionnaire in order to examine the improvement effect on swallowing a crude drug product in food. The screening tests were carried out to reveal what kinds of foods could improve the taste and texture of the crude drug product by mixing them with 30 kinds of foods. In the screening test, a statistically significant effect was observed on masking bitter taste. Based on this screening test, the bitterness masking tests were carried out with 6 kinds of foods. As a result, a commercially available swallowing aid jelly, vanilla ice cream, chocolate ice cream, condensed milk, peanut cream, and seaweed tsukudani significantly reduced the bitterness of the crude drug product. The tastes of these foods are strong, so it is necessary for patients with sugar and salinity limitations to consider the usage of these foods. These foods are relatively inexpensive and easy to obtain. Therefore, they might be useful for patients to take medicines such as bitter crude drug products following the instructions of a physician.