著者

矢田 登

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.38, no.3, pp.275-287, 1980-03-01 (Released:2009-11-13)

参考文献数

45

被引用文献数

1 1

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Recent advances of prodrug formation of therapeutic agents were reviewed with 44 references in terms of (1) improvement of stability, (2) masking of bitter taste, (3) increase of water solubility, (4) improvement of bioavailability, and (5) selective distribution into the site of action.Basic consideration for rational design of prodrug was also presented.