著者

湧井 宣行 大久保 哲生 岩崎 雄介 伊藤 里恵 小林 岳 早川 和宏 三井 みゆき 矢野 裕一 斉藤 貢一 中澤 裕之

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.37, no.7, pp.425-430, 2011 (Released:2012-08-30)

参考文献数

9

被引用文献数

6 4

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The pulverization of tablets for the preparation of pediatric medicines causes problems with respect to content uniformity and amount of the main ingredient. We compared these 2 factors in a pediatric medicine prepared by 2 methods: tablet grinding and tablet dilution. We also investigated causes of drug loss by means of high-performance liquid chromatography (HPLC).Three pharmacists prepared cortril powder by each method. When the main ingredient content was calculated by quantitative analysis by means of HPLC, there was no significant difference between the 2 methods, and adhesion to the mortar and the package were considered to be major reasons for drug loss.We also examined the effect of the amount of diluent on the loss of the main ingredient in the grinding process, finding that increasing the amount of diluent minimized the loss of the main ingredient content. When the amount of diluent per package was 1.5g, the main ingredient content was 90.8% (n=3).These results suggest that when dispensing small amounts of ground tablets, more attention should be paid to the amount of diluting agents than to the grinding technique.

著者

田中 駿 矢野 裕一郎 二宮 崇 高村 大也

出版者

人工知能学会

雑誌

人工知能学会全国大会論文集 (ISSN:13479881)

巻号頁・発行日

vol.28, 2014

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本研究はBBS(電子掲示板)要約の問題を整数線形計画問題として解く手法を提案する。BBS要約は文章要約の一種であり、BBSの記事から重要な投稿だけを抽出することにより要約が生成される。一般の文章要約では字数制限を整数線形計画問題の制約とすることができるが、BBS要約には字数制限がないため、一般の文章要約の手法はそのままでは適用できない。本研究では記事に応じて投稿数の制限を与える手法を提案する。

著者

吉田 栄子 大川原 美紀 劉 亦韋 矢野 裕一 喩 静 川崎 力 秋本 義雄 平賀 秀明

出版者

日本社会薬学会

雑誌

社会薬学 (ISSN:09110585)

巻号頁・発行日

vol.39, no.2, pp.79-86, 2020-12-10 (Released:2020-12-30)

参考文献数

28

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China’s pharmaceutical market, the second largest in the world, has recently attracted the attention of many countries. However, Chinese pharmacists’ role in pharmacies and their legal responsibilities in China are not well known in Japan. Clarifying Chinese pharmacists’ legal obligations and identifying their specific roles may contribute to improvements in pharmacy operations in Japan. To investigate the Chinese legal system as it pertains to pharmacists in China, we used China’s official government website. In 2019, there were 516,003 pharmacists in China. As of 2020, the Chinese Pharmacist Act is still in the preparatory stage; however, the Administrative Regulation, which describes the system for licensing pharmacists, has been established. Article 1 of the Administrative Regulation states that Chinese pharmacists are responsible for the quality control of medications, as well as medication consultations. Another regulation, Good Supply Practice, specifies that the lot numbers of medications should be provided to patients at the time of dispensing. We believe that this is particularly beneficial to pharmaceutical traceability. Since 2017, the circulation of counterfeit HARVONI® combination tablets has been a problem in Japan. To secure and improve the quality of medications in Japan, we believe that it is important for pharmacists to understand that they are “responsible for the quality of the medicine” and to promote discussions on pharmacy quality control tasks.