著者

福富 久之 吉田 茂昭 河村 譲 平嶋 登志夫 吉森 正喜 小黒 八七郎 広田 映伍 崎田 隆夫

出版者

一般社団法人 日本消化器内視鏡学会

雑誌

日本消化器内視鏡学会雑誌 (ISSN:03871207)

巻号頁・発行日

vol.19, no.4, pp.408-417, 1977 (Released:2011-05-09)

参考文献数

26

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Clinical and histological studies on gastric carcinoma has been reported by many authors, but we have as yet limited information of gastric carcinoma in the young with special reference to early stage. In this paper 50 cases of gastric carcinoma patients less than 30 years of age in our hospital during 15 years period from 1962 to 1976 will be reported with comparative statistics. The cases were divided into two groups. One is the early carcinoma group in which cancerous invasion limited within submucosal layer. Another is the advanced carcinoma group in which deeper cancerous invasion than submucosal layer was detected. The incidence of gastric early carcinoma in the young was in 10 (1.4%) of 737 patients detected by gastric resection, and in 6 (1.2%) of 481 male and 4 (1.6%) of 256 female with early gastric carcinoma. As the initial symptoms in early gastric carcinoma group, gastric pain were present in 800. The duration of the symptoms were less than 6 months in 20% and longer than 1 year in 400. Macroscopically, all cases were of depressed type (IIc or IIc+III). Protruded type (I, IIa) early carcinoma could not be found in the young. Histologically, 9 out of 10 cases showed mucocellular adenocarcinoma, mostly having ulcer and ulcerscar in the center of depressed cancerous invasion. The degree of cancerous invasion was 6 in the mucosal layer and 4 in submucosal layer and no lymphatic metastasis was found except 1 case. Young early carcinoma was most often seen on the lesser curvature side, especially in the middle portion. Distribution pattern of intestinal metaplasia in the surrounding mucosa of gastric carcinoma was examined histologically, and metaplasia were shown in 6 cases of 10 specimens. In advanced carcinoma group, 40 cases of advanced carcinoma were studied, and this corresponds to 1.8 percent of all surgical cases in our experience. The female outnumbered male in ratio of 23 to 17. Gastric resection was performed in 31 of the 40 patients treated by laparotomy, and in 16 of 17 male, 15 of 23 female with laparotomy. Macroscopically, Borrmann f, Borrmann iV type carcinoma were predominantly found compared with other age groups. Especially Borrmann IV diffused type was seen in 320. We have no case of Borrmann I type which were found frequently in old patients. Lymphatic metastasis is positive in 34 cases of 40 cases. Histological investigation revealed mucocellar adenocarcinoma in 740. The entire stomach or middle portion of the stomach was predominantly involved region in advanced carcinoma group similar to that of early carcinoma group. Five year survival rate was noted in 200 of the 31 resectable cases of advanced carcinoma. Further studies of a greater number of gastric carcinoma in the young might be necessary.

著者

池澤 和人 樫村 博正 三代 寧 中原 朗 山形 迪 松崎 靖司 武藤 弘 福富 久之 大菅 俊明 折居 和雄 深尾 立 菊池 正教

出版者

一般社団法人 日本消化器内視鏡学会

雑誌

日本消化器内視鏡学会雑誌 (ISSN:03871207)

巻号頁・発行日

vol.37, no.5, pp.1019-1027, 1995-05-20 (Released:2011-05-09)

参考文献数

17

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症例は41歳女性.29歳より計5回の甲状腺乳頭癌の手術歴があり,1992年7月腹痛のため当科を受診した.下部消化管精査の結果大腸全域にびまん性の腺腫性ポリープが密生し,また,横行結腸に全周性の内腔狭窄を併う2'型大腸癌,S状結腸に1'型大腸癌,下行結腸にIsp'型大腸癌を認めた.胸部X線,肺CTにて3カ所に小結節陰影が認められ,大腸癌及び甲状腺乳頭癌の肺転移を伴った家族性大腸腺腫症と診断し,全結腸切除回腸直腸吻合術及び肺部分切除術を施行した.家族性大腸腺腫症は放置すればほぼ100%大腸癌に罹患することが知られているが,甲状腺乳頭癌を重複した報告は稀であり,文献的考察を加えて報告した.