著者

竹内 智一 田中 裕幸 藤岡 英二 植野 彰規

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.55, no.6, pp.267-271, 2017-12-10 (Released:2018-03-29)

参考文献数

12

被引用文献数

2

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In this study, we developed a new approach for simultaneous noncontact measurements of electrocardiograms (ECGs) and pulse beats (PBs) using passive and semi-active capacitive-coupling methods. The applicability of this method to blood-pressure (BP) monitoring of subjects in bed was then evaluated. For ECG measurements, two sets of five-layered conductive-cloth electrodes were placed under the subject's upper back and waist. A so-called driven-seat ground (DSG) was adopted for ECG measurements to reduce interference with the PB detection circuit. The DSG signal was fed back to the fifth layer of the electrode. For PB detection, one conductive cloth sheet was placed under the right calf and another under the right heel. The sheets formed capacitive couplings with the body via clothing, and the couplings were incorporated into a multi-vibrator. Changes in the oscillatory frequency of the multi-vibrator caused by PBs were measured as voltage changes. To increase the sensitivity of PB detection under the heel, the sheet area ratio between the calf and the heel was set to 5:1. Seven participants were instructed to lie on a bed in the supine position, and experimental measurements were performed on them. In the experiment, the following procedures were conducted : the subject rested for 20 s;a Valsalva test (VT) was conducted for 15 s;and the subject rested again for 100 s. As reference signals, continuous measurements of BP from the left fingertip, as well as chest ECG and photo-plethysmographic signals from the right fingertip were recorded. For evaluation analysis, all PBs were detected over the 80-second period of the output signals beginning 10 seconds after the end of the VT. As a result, the sensitivity of the PB was 99.2±1.1%. The mean correlation coefficient between the PB arrival time and systolic BP was-0.83±0.15. These results suggest the possibility of using the proposed method for noncontact BP monitoring during rest in bed.

著者

並木 祐子 林 孝彰 奥出 祥代 竹内 智一 北川 貴明 月花 環 神前 賢一 久保 朗子 常岡 寛

出版者

JAPANESE ASSOCIATION OF CERTIFIED ORTHOPTISTS

雑誌

Japanese orthoptic journal (ISSN:03875172)

巻号頁・発行日

vol.39, pp.123-128, 2010-12-29

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<B> 目的:</B>小口病は常染色体劣性の遺伝形式をもつ先天停在性夜盲の一つで、視力、視野、色覚に異常はないと考えられている。以前、我々が報告した錐体機能低下および進行性の視野障害をきたし、<I>SAG</I>(アレスチン)遺伝子変異(1147delA)を認めた高齢者小口病の1例(臨床眼科 63:315-21, 2009)について、今回は、黄斑部機能、色覚について検討したので報告する。<BR><B> 症例:</B>70歳、男性。矯正視力は右(1.2)、左(1.5)、Humphrey視野(中心10-2全点閾値)の中心窩閾値は良好であった。スペクトラルドメイン光干渉断層計所見として、中心窩付近の視細胞内節外節接合部ラインは明瞭であったが、それ以外の部位では不明瞭であった。錐体機能を反映する黄斑部局所網膜電図で、a波およびb波とも著しい振幅低下を認めた。片眼ずつ色覚検査を行い、石原色覚検査表国際版38表では誤読数が右4/21、左3/21と成績は良好であった。Panel D-15では両眼ともpass(no error)であったが、Farnsworth-Munsell 100 hueテストにおいては、青黄色覚異常の極性に一致し、総偏差点は右268左292と年齢によるスコアを超える異常値を示した。<BR><B> 結論:</B><I>SAG</I>遺伝子変異(1147delA)陽性小口病の中には、黄斑部錐体機能が低下し、経過中に典型的な後天青黄色覚異常を呈するものがある。