著者

綾田 渙

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.81, no.5, pp.778-783, 1961-05-25 (Released:2010-02-19)

参考文献数

11

被引用文献数

1

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Resolution of dl-(2-hydroxy-3-cyanopropyl) trimethylammonium chloride (III) was carried out with d-tartaric acid or dibenzoyl-d-tartaric acid, and dextro- and levorotatory compounds of (III) were obtained. Hydrolysis of these optically active (III) with conc. hydrochloric acid by heating in a boiling water bath afforded the corresponding d- and l-(2-hydroxy-3-carboxypropyl) trimethylammonium chloride (VII). Of these, the levorotatory (VII) was found to correspond to the hydrochloride of natural carnitine (VIII). Infrared spectra of these compounds are given.