著者
小林 裕章 金子 剛 西本 紘嗣郎 内田 厚
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.56, no.1, pp.63-65, 2010-01

Penile strangulation is one of the emergent urologic disorders, because immediate release is the critical treatment to prevent penile necrosis, urethral injury, erectile disorder, and other unfavorable events. A 66- year-old man was transferred to the emergency room of our hospital for the penile swelling and pain, occurring by penile insertion to the beverage bottle for masturbation. The penis was completely relieved using an electric plaster cutter without any injury. The strangulation time was four hours and a half, and there were no complications. We recommend an electric plaster cutter as a useful tool for this incident.
著者
小林 裕章 金子 剛 西本 紘嗣郎 内田 厚
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.55, no.12, pp.749-752, 2009-12

Pheochromocytoma occurs in 0.1 to 5.7% of patients with type 1 neurofibromatosis (NF1). Radiological findings of pheochromocytoma are often similar to those of neurofibroma ; therefore, any pheochromocytoma should be excised in hypertensive patients with NF1. A 60-year-old male patient with NF1 was referred to this hospital for an incidentally discovered right adrenal mass, 7×6 mm indiameter. The patient had multiple benign tumors and suffered from hypertension for 4 years. Laboratory findings showed increased serum and urine catecholamine levels. Magnetic resonance imaging (MRI) revealed a high signal intensity on T2-weighted images, which was enhanced by gadolinium contrast. The mass was positive for 131 I-metaiodobenzylguanidine (MIBG) scintigraphy. A laparoscopic adrenalectomy was performed. A histopathological diagnosis of pheochromocytoma was made. The patient's post-operative course was uneventful, and blood pressure was normalized. Screening of the adrenal tumor is strongly recommended for NF1 patients with hypertension, since any unfavorable events due to catecholamine such as cardiomyopathy and fatal arrhythmia can be avoided by adequate surgical intervention.
著者
小林 裕章 金子 剛 西本 紘嗣郎 内田 厚
出版者
泌尿器科紀要刊行会
雑誌
泌尿器科紀要 (ISSN:00181994)
巻号頁・発行日
vol.56, no.1, pp.63-65, 2010-01
被引用文献数
0 or 1

Penile strangulation is one of the emergent urologic disorders, because immediate release is the critical treatment to prevent penile necrosis, urethral injury, erectile disorder, and other unfavorable events. A 66- year-old man was transferred to the emergency room of our hospital for the penile swelling and pain, occurring by penile insertion to the beverage bottle for masturbation. The penis was completely relieved using an electric plaster cutter without any injury. The strangulation time was four hours and a half, and there were no complications. We recommend an electric plaster cutter as a useful tool for this incident.
著者
向井 邦晃 三谷 芙美子 西本 紘嗣郎
出版者
慶應義塾大学
雑誌
基盤研究(C)
巻号頁・発行日
2009 (Released:2009-04-01)

低分量基底膜蛋白質であるAZ-1は、血管基底膜の構成因子として構造的細胞外マトリックス蛋白質、血管内皮増殖因子、同受容体、インテグリン群との結合能を持つ多価相互作用因子であることが判明した。この相互作用が血管内皮細胞の接着、増殖、管腔形成などを制御することにより、血管内皮増殖因子による細胞の活性化が抑制されて血管内皮の恒常性が維持されうることが示唆された。